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Similarly, HMGB1, another proinflammatory molecule, increased seizure frequency in rats after injection into the hippocampus (166)
The ratio of target-receptor agonism can be manipulated to maximise efficacy whilst optimising adverse effects [31]
Extremely rare occurrences of ribose-5-phosphate isomerase and transaldolase deficiency have also been documented
In functional medicine, OAT is interpreted alongside clinical history, symptoms, and other investigations rather than used as a standalone diagnostic tool