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Discussion Type 2 diabetes (T2D) is one of the most common metabolic disorders

This powerhouse molecule has the remarkable ability to neutralize harmful free radicals, safeguarding liver cells from oxidative stress and damage

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Such buffering could for example be mediated by activation of the Nrf2-Keap1-ARE pathway, which has been shown to be increased after polyphenol supplementation which in turn induces the expression of phase II detoxifying enzymes, responsible for reducing endogenous toxic metabolites [65]