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Principles of the use of new therapeutic options, i.e., mipomersen [355] or PCSK9 inhibitors, have not yet been established in children, although in treatment of familial hypercholesterolaemia, these agents provide some hope for the future, especially when studies with alirocumab and evolocumab have been completed in children with both homo- and heterozygous FH

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Its best to split the dosage in half throughout the day to avoid any gastric complications