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The specific G6PDH inhibitory effect of these compounds may be exploited for the treatment of human diseases with high NADPH and GSH consumption rates, including malaria, trypanosomiasis, cancer or obesity

Due to the potential for soy isoflavone supplements (which may contain higher concentrations of isoflavones than found in food) may affect certain hormones, including estradiol and thyroid hormones, and therefore are generally not recommended for pregnant or nursing women (Franke, Am J Clin Nutr 2006

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