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Additionally, it features structural modifications that significantly extend its half-life

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Up to 80-90% of miscarriages occur during this time, with the risk being much lower in the second trimester

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The report was uncontrolled, unblinded, not randomized, had no comparator arm, used patient-reported outcomes rather than validated pain instruments, and did not publish dose, effect size, confidence intervals, p-values, or systematically collected adverse events limitations that severely constrain any clinical inference