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Despite its essential role in life, excessive iron is toxic due to its ability to generate ROS and to trigger cell death

With a binding affinity to hepatocyte growth factor (HGF) that promotes synaptogenesis at rates seven orders of magnitude higher than brain-derived neurotrophic factor (BDNF), Dihexa represents a fundamentally different approach to neuroplasticity research

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Elevated levels indicate oxidative stress

Cells 10(11):3259 De Las HN, Lahera V (2022) Relevance of mitochondrial dysfunction in heart disease associated with insulin resistance conditions