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& Biswal, S

& Corominas, M

However, these studies also highlight important challenges in clinical translation, particularly regarding interindividual variability in response and the need for optimized delivery strategies

The intracellular glutamate concentration is nearly 10-fold higher than the Km value, but intracellular cysteine concentrations approximate the apparent Km value [10] indicating that cysteine may be a limiting substrate for GCL

Overlapping antioxidant response element and PMA response element sequences mediate basal and beta-naphthoflavone-induced expression of the human gamma-glutamylcysteine synthetase catalytic subunit gene