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Deficient synthesis of glutathione underlies oxidative stress in aging and can be corrected by dietary cysteine and glycine supplementation

TLK286 L--Glutamyl-3-(bis[bis(2-chloroethyl)amino-phosphinyl]oxy)ethylsulfonyl-L-alanyl-2-phenyl-[2 R ]-glycine hydrochloride salt (TLK286) represents the most promising GST-prodrug candidate

Glutathione transferases in bacteria

One of its remarkable features is the presence of a sticky sulfur chemical group that collects and neutralizes harmful molecules floating in the body

When intracellular GSH levels were depleted activation of caspase 3 was less, being 30 and 40% for AQ-QI and DEAQ-QI, respectively