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17 In addition to these findings, the SUSTAIN-6 trial also showed that semaglutide can offer a significant reduction in the risk of new or worsening nephropathy including persistent macroalbuminuria, increase in serum creatinine or the need of renal replacement therapy

The 10 ng/kg minimum effective dose established BPC-157 as among the most potent cytoprotective peptides identified from endogenous sources at that time

34 , 15141531.e1517 (2022)

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However, Hinge did effectively inhibit spine formation in neurons stimulated with 10 ng/ml HGF (Figure 13B), 10 " 12 M Nlel-AnglV ( Figure 13C) or lO "12 M Dihexa ( Figure 12D) further supporting the contention that these actions are mediated by the HGF/c- Met system