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Herbrich S, Baggerly K, Alatrash G, Davis RE, Andreeff M , Konopleva MY

doi: 10.1038/nature12048 271 SanchezT.SkouraA.WuM

In many cases they possess an N-terminal signal peptide mediating correct subcellular sorting and trafficking and an anionic propeptide which is thought to be the major contributing factor inhibiting the antimicrobial activity by neutralizing the net positive charge of the mature peptide [19, 20]