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Appraisal of CagriSema for treatment of obesity and type 2 diabetes 1.Advantages of CagriSema Available data suggest that the HbA1c-lowering efficacy of the combination of cagrilintide and semaglutide was higher than that achieved by each drug alone (table 1) [10]

Cagrilintide is a long-acting synthetic analogue of human amylin

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In the last decades, IGF-1 has been implicated in many physiological actions, among others: tissue growth and development, proliferative, lipid metabolism, pro-survival/anti-aging, anti-inflammatory, anabolic, and antioxidant with neuro- and hepatoprotective properties [105116]