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There is a glaring lack of direct, large-scale human clinical trials studying this specific combination

Even though mitochondrial dysfunction appears evident in ME/CFS, the causes of such dysfunction are speculative (251) and there is inconsistent evidence correlating mitochondrial dysfunction and ME/CFS (254, 283, 386, 389, 419)

Pretreatment with coenzyme Q10 improves ovarian response and embryo quality in low-prognosis young women with decreased ovarian reserve: a randomized controlled trial