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10.3389/fcell.2021.756315 Front Cell Dev Biol

Although some studies have demonstrated benefits such as increased lean body mass and improved body composition (in populations with clinical need for the drugs), these gains have not consistently translated into enhancements in muscle strength, physical performance, or overall quality of life

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Cagrilintide is a long-acting amylin analogue that reduces appetite and slows gastric emptying, whilst retatrutide is a triple GLP-1, GIP, and glucagon receptor agonist designed to reduce appetite and increase energy expenditure

This allows the liposomal delivery to work without being slowed down by a heavy meal