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Standard wound care (cleaning, appropriate dressing, addressing underlying causes) takes precedence

Zhang and Ney, 2010)

Studies have suggested that higher doses might become necessary for significant health advantages, but they should be taken under medical supervision

We stated that we believe balancing our preference to use the latest available data from the MedPAR files and stakeholders' concerns about being able to use publicly available MedPAR files to review the charge inflation factor can be achieved by modifying our methodology to use the publicly available Federal fiscal year period (that is, for FY 2020, we used the charge data from Federal fiscal years 2017 and 2018), rather than the most recent data available to CMS which, under our prior methodology, was based on calendar year data

In addition, they also showed a significant increase in tubular cells positive for FOXO4 foci (Fig