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This hypothesis was subsequently validated in experiments using RAW264.7 mouse macrophage-like cells and in mice infected with Bacillus Calmette-Gurin (BCG)

The blood samples were kept at room temperature for 30 min to clot

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Luteolin selectively inhibits the type of O-glycosylation (Mucin-type O -glycosylation) involved in the formation of amyloid- .[ref] Animal studies show luteolin inhibits neuroinflammation by controlling microglia activation.[ref] In a mouse study of Alzheimers, luteolin protects against amyloid memory dysfunction and also increases levels of endogenous antioxidants, including Mn-SOD, Cu/Zn-SOD, and glutathione

KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney disease