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High-dose oral therapy (10002000 micrograms daily) can be effective even in pernicious anaemia, as approximately 1% of B12 is absorbed through passive diffusion independent of intrinsic factor

Doses tested were 250mg once daily, 250mg twice daily, and 500mg once daily and all three showed a statistically significant reduction in melanin index compared with placebo, measured using a handheld device called a mexameter

TB-500 promotes cell migration to injury sites, reduces inflammation, and improves flexibility of healing tissue

M., Karoly, E

Glutathione peroxidase 1 protects against peroxynitrite-induced spiral ganglion neuron damage through attenuating NF-B pathway activation