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(GLP-1 weight-loss drugs, which are peptides, have been thoroughly tested and FDA-approved.) Proponents of these peptide therapies contend they have a better safety profile because they're known compounds that our bodies already make

Understanding these mechanisms is essential for interpreting the breadth of effects reported across preclinical studies

R 2 is H, C 1 -C 6 alkyl, C 1 -C 6 alkyl-NR 5 R 6 , C 1 -C 6 alkyl-OR 5 , or C 1 -C 6 alkylC 3 -C 6 cycloalkyl

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