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UA is the final metabolite of purines and mainly excreted in the body by the kidney and intestine

We also found that auranofin is an efficient inhibitor of pure TGR ( K i = 10 nM), able to kill parasites rapidly in culture at physiological concentrations (5 M), and able to partially cure infected mice (worm burden reductions of ~60%)

It also states that available safety information is insufficient to know whether harm could occur

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