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The alterations observed in lipid metabolism in patients with GWS and ME/CFS suggest potential mitochondrial dysfunction, which may underlie the profound fatigue characteristic of these conditions (Germain et al., 2018, 2020, 2022

BPC 157 (10 g/kg and 10 ng/kg), L-NAME (5 mg/kg), and L-arginine (100 mg/kg) were administered per se or combined with each other while controls were administered equivolume saline (5 mL/kg) intraperitoneally

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