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2016 trial administered 1,200 mg twice weekly for 6 weeks, totaling 12 injections

People with chronic diseases had lower mean GSH concentrations than those who were free of disease

With intestinal disease (including bypass operations that may be performed to treat obesity), increased fecal loss of bile acids leads to decreased concentrations of both primary and secondary bile acids and, often, a decrease in cholesterol caused by increased need for bile acid synthesis

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