Wilsons disease is a contraindication
PLoS One 11 (7), e0158235
Biochemical evaluation of glutathione typically includes confirmation of compound identity, purity assessment using advanced chromatographic techniques, and stability testing under controlled laboratory conditions
J Leukoc Biol 52:135142 Blomberg OS, Spagnuolo L, Garner H, Voorwerk L, Isaeva OI, van Dyk E, Bakker N, Chalabi M, Klaver C, Duijst M et al (2023) IL-5-producing CD4(+) T cells and eosinophils cooperate to enhance response to immune checkpoint blockade in breast cancer
As the immune system takes priority in survival, insufficient glutathione may express itself as fatigue since skeletal muscles cannot sustain normal aerobic metabolism