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Front Med (Lausanne) (2020) 7:607725

Caspase-3, cystein-asparate protease 3

Joseph P

Mitochondrial damage can trigger mitochondrial DNA (mtDNA) release, activating the cGAS-STING1 pathway and potentially contributing to ferroptosis, as observed with inducers like zalcitabine (116)

If approved , cagrilintide could become a first-line option in pharmacologic obesity management , especially within aesthetic settings where facial fullness, contouring, and body composition improvements are key patient goals