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S-ACE2 interaction and subsequent fusion are followed by the reconstitution of the luciferase, whose activity serves as a read-out for S protein fusogenicity

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Despite their promising effects and low cost, TCAs should be prescribed cautiously because of the side effects such as dry mouth, constipation, urinary retention, and orthostatic hypotension

Increases in muscle strength ranged from 24-62% depending on the muscle group

Its Innovative Science and Technology Approaches for New Drugs (ISTAND) pilot program is explicitly considering complex in vitro models like OoCs, with a liver-on-chip for DILI being the first OoC accepted into the program for evaluation (222)