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It has also been demonstrated to impair the uptake of essential amino acids by the transporter protein SLC38A2, thereby decreasing the cellular levels of these nutrients [175]

Sistema gastrointestinal : - Sikiric et al

Additionally, it downregulates SLC7A11 channel protein expression while upregulating ALOX3, further promoting ferroptosis ( Multiple studies have also revealed that Saikosaponin A can induce ferroptosis in hepatocellular carcinoma (HCC) cells, both in laboratory settings and in living organisms