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You do not start at the maximum dose

Its naturally found in animal-based foods like meat, poultry, fish, eggs, and dairy and its added to some fortified cereals, plant-based milks, and nutritional yeast [*]

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Of the 14 semaglutide-treated patients that developed anti-semaglutide antibodies, 7 patients (0.2% of the overall population) developed antibodies cross-reacting with native GLP-1