Polyphenols, found in foods like green tea and red wine, possess potent antioxidant activity and have been linked to reduced risks of chronic diseases [197]
mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6
Resveratrol is an agent with properties that should be investigated in other studies and settings
This review summarizes the molecular characteristics and antioxidant functions of GPX4, evaluates experimental evidence linking GPX4 and ferroptosis in OA, outlines upstream and downstream molecular mechanisms regulating GPX4, and summarizes therapeutic strategies targeting GPX4, including pharmacological, gene, and combination therapies
Johns wort, can raise your blood pressure or negatively interact with medication Image content: This image is available to view online