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This biochemical synergy is one reason why Pinealon effects on mood tend to become more pronounced over the four-to-six-week timeline, as the circadian system progressively normalizes

It explains why a molecule with 3 amino acids can have such a broad effect in different tissues

Data Availability: All relevant data are within the paper and its Supporting Information files

For more substantial or chronic conditions (e.g., tendon injuries or longstanding inflammation), treatments may last 46 weeks to see full or peak effects, and some individuals may require longer cycles for maximal benefit

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