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22,23 Nonetheless, it is unknown whether losing weight will improve outcomes in people with obesity and CKD

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This study confirmed that macrophages secreted NO to adjacent epithelial cells, preventing phospholipid peroxidation in epithelial cells, thereby inhibiting ferroptosis, while NO expression did not affect intracellular GPX4 levels

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The clearest direct evidence comes from a double-blind, crossover study in 16 healthy adults who received GHB alone, alcohol alone, both together, or a placebo