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Additionally, the exploration of pathophysiological-related entities could enrich the present perspectives and enhance our understanding of the underlying mechanism, taking, for instance, NMDA-R encephalitis as a valid comparative model for SZ

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Ageing and inherited genetic variants affecting enzymes involved in one carbon metabolism, including MTHFR , may further reduce the efficiency of methylation

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This intermediate promiscuity likely reflects the partial exposure of the hydrophobic core in Syn S129E , which may contribute to LB formation