Using a primary rat hepatocyte-based model, both aliphatic (e.g., sulforaphane, AITC) and aromatic (e.g., BITC, PEITC) isothiocyanates (at 20-40 M) have been found to downregulate CYP3A2 mRNA expression, as well as the activity of benzyloxyquinoline debenzylase, a marker of CYP3As (22)
Khi kt hp cng vitamin C, hiu qu chng oxy ha v h tr lm sng da cng c ti u hn, do vitamin C gip ti to glutathione trong c th
Animal studies demonstrate that heavy metal exposure significantly depletes hepatic glutathione levels while increasing GST enzyme activity as a compensatory response
The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
doi:10.1210/jc.2005-1536 Compliance Statement This product is intended for laboratory research use only and is not approved for human or veterinary use.