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However, it is an INCI-listed cosmetic ingredient widely used in skincare formulations

10.1016/j.jgr.2019.05.005 49 JanetzkyK.MorrealeA

In assessing the CGI-I, one subject scored a 4 (no change/improvement), four subjects scored a 3 (minimally improved), and one subject scored a 6 (much worse)

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Anti-Inflammatory Properties Both peptides exhibit inflammation-modulating effects through different mechanisms: BPC-157 appears to influence inflammatory pathways by: Regulating cytokine expression Modulating nitric oxide systems Supporting vascular integrity during inflammation Protecting against NSAID-induced damage TB-500 contributes through: Reducing inflammatory cell infiltration Modulating immune responses Supporting tissue remodeling post-inflammation Decreasing oxidative stress markers This dual-action approach makes the combination particularly valuable for those dealing with chronic inflammatory conditions or acute injury recovery