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Plasmodium culture media is optimized to mimic physiological blood conditions, while Ringer is a nutrient-poor solution

Additionally, while some may tolerate a high amount of caffeine, many will experience side effects, including hormone changes and sleep disturbance

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Hydrogenation was completed using the AutoDock (version 1.5.7), and the molecular docking processes were achieved through AutoDock Vina (version 1.2.5) with the grid boxes parameters (Table S2)

A prior study revealed that co-culture of Th17 cells with MSCs reduced pro-inflammatory cytokine secretion whilst promoting the spread of anti-inflammatory cells, thereby reducing the pathogenicity of Th17 cells (131)