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The underlying protective mechanisms for CoQ10 against natural and chemical compound toxicity included the enhancement of antioxidant enzyme activities such as superoxide dismutase, catalase, glutathione peroxidase, glutathione-S-transferase, and suppression of pro-inflammatory markers such as tumor necrosis factor-alpha, interleukin-1, and IL-6

Mikelsaar et al

In the long run, these ROS-mediated effects might influence the rheological properties of erythrocytes, thereby demonstrating the clinical relevance of eryptosis research [118]

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Conjugation of aliphatic ITCs with glutathione, the further processing of these conjugates and the molecular mechanism of ITC-triggered reduction of glutathione levels in planta still requires further investigation