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The key outcome measures were GSH levels in various body compartments, including blood, erythrocytes, plasma, lymphocytes, and exfoliated buccal mucosal cells

Every escalation decision is reviewed by an independent Safety Review Committee, which evaluates all available data against predefined stopping rules

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Hereditary cancer syndromes like BRCA1/2 mutations, Lynch syndrome, and Li-Fraumeni syndrome create elevated lifetime cancer risk that persists regardless of current cancer status

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