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Performing carpal tunnel release (CTR) under the guidance of ultrasound was first documented in 1997

The tissue lacks the robust blood supply that muscles enjoy, receives constant mechanical loading that disrupts healing, and often develops fibrotic scar tissue rather than healthy organized collagen

The pain is usually localized to the injection site and may be accompanied by stiffness or weakness in the affected arm

Failure of DNA repair induces apoptosis through p53 activation, mitochondrial pathway induction, and persistent DNA damage response (DDR) signaling 8-10

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