Our screening platform provides a pathway to uncover host-directed therapies that synergize with antibiotics to clear intracellular persisters
Some clinical isolates from patients with head and neck cancer exhibit moderate to high fluconazole tolerance, with high-tolerance strains upregulating ERG11 , CDR1 and other genes to maintain biofilm integrity and drug survival under antifungal pressure (Hatami et al., 2023)
The expression of COX-IV, a subunit of COX translocation protons, was high not only in ductal epithelial cells in the control group but also in the immune cells of lymphoid infiltrating lesions in the pSS group ( Figure 6B )
Take capsules with water before meals
Similarly, the binding site of fluoxetine to MRP7 (Figure 3, right panel, middle row) is composed of hydrophobic residues, polar residues, and glycine residues