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Notably clinical studies carried out in 1997 directly demonstrated that low GSH levels in CD4 T cells predict poor survival in otherwise indistinguishable HIV-infected subjects ( N -acetyl cysteine restored GSH blood levels, suggesting the use of this drug for HIV treatment and improving survival

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Large clinical trials have not consistently shown that isolated antioxidant supplements prevent cardiovascular disease in generally well-nourished populations

N -Acetylcysteine mucolysis in the management of chronic obstructive pulmonary disease