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Additionally, patients with inflammatory bowel disease, severe gastroesophageal reflux disease, or other significant gastrointestinal disorders should be monitored closely if treatment is initiated, as the gastrointestinal effects of semaglutide may worsen their underlying condition

This is why we strongly recommend: Using a cycling protocol (periods of use followed by planned breaks) rather than continuous, indefinite use

What happens if your B12 is too high

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