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These animals were housed under controlled environmental conditions and had free access to food and water [1]

FIGURE 1 Although bona fide prions (prions having full infectious life cycle from host to host) are rare (Scheckel and Aguzzi, 2018), the ability of a protein to form self-perpetuating aggregates appears to be at play in a much broader range of human pathologies including Alzheimers disease (AD), Parkinsons disease and amyotrophic lateral sclerosis (ALS) (Prusiner, 2012