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Accordingly, Wistar rats were divided into nine groups of six including sham, negative control group (CCI), positive control group gabapentin (100 mg/kg), AST (5, 10 mg/kg), flumazenil (0.5 mg/kg), naloxone (0.1 mg/kg), AST (10 mg/kg) + flumazenil (0.5 mg/kg), and AST (10 mg/kg) + naloxone (0.1 mg/kg) were administered intraperitoneally on days 1, 3, 5, 7, 10, and 14

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In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference

These findings demonstrate that UA treatment provokes the antioxidant system in macrophages leading to increased expression of the enzymes involved in the so-called glutathione system

Higher doses can produce more serious, potentially life-threatening effects (Figure 3)