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Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection

Mol Brain Res 28(2):281295 Ikeda A, Nishioka K, Meng H, Takanashi M, Hasegawa I, Inoshita T, Shiba-Fukushima K, Li Y, Yoshino H, Mori A, Okuzumi A, Yamaguchi A, Nonaka R, Izawa N, Ishikawa KI, Saiki H, Morita M, Hasegawa M, Hasegawa K, Elahi M, Funayama M, Okano H, Akamatsu W, Imai Y, Hattori N (2019) Mutations in CHCHD2 cause -synuclein aggregation

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1 Introduction The growing global burden of cancer necessitates innovative strategies that span prevention, treatment sensitization, and mitigation of therapy-related toxicity ( Epidemiological studies have consistently linked the consumption of glucoraphanin-rich cruciferous vegetables with a reduced risk of several cancers, including those of the prostate, lung, and colorectum ( The efficacy of SFN is intrinsically linked to the biosynthesis of its precursor, glucoraphanin, in the plant itself