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Interestingly, the observation that other amino acids than V12 and F112 can principally support flavonoid binding is also reflected in the more relaxed amino acid conservation in native arGSTFs at these two positions (Fig

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[PubMed: 25537186] (Review of acetaminophen hepatotoxicity focusing upon pathophysiology [CYP 2E1 metabolism], risk factors [decrease in glutathione or upregulation of CYP 450], clinical presentation, management [NAC, and use of Rumack-Matthew normogram], liver support systems, liver transplantation and outcomes)

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doi: 10.3892/etm.2017.5106 262 MizunoMMinatoKI

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Role of -MSH and Melanin Production -MSH plays a central role in regulating melanin production

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