10.3109/10520295.2013.811285 [DOI] [PubMed] [Google Scholar] Schulze-Tanzil G., De Souza P., Villegas Castrejon H., John T., Merker H
Wolfe GI, Ward ES, de Haard H, Ulrichts P, Mozaffar T, Pasnoor M, et al
In primary tumors subjected to indirect immunofluorescence a variable number of tumor cells (2575%) showed positive cytoplasmic labeling after incubation with DSIP antiserum
This finding reinforced the in vivo observations, demonstrating that Gepon directly downregulates inflammatory cytokine production in monocytes
These results suggest that while mechanistic synergy is plausible, clinical translation may be context-dependent, influenced by baseline health status, intervention intensity, duration, and population characteristics