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Both compounds have been studied in mixed-gender populations

It is primarily associated with side effects such as nausea, increased heart rate, hyperhidrosis, constipation, urinary hesitation, sexual dysfunction, and potential increases in blood pressure (Asnis and Henderson 2015)

Pretreatment with 10 g/g GHK-Cu significantly reduced the phosphorylation of both NF-B p65 and p38 MAPK, and slightly decreased JNK1/2 phosphorylation, with no effect on ERK1/2