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This mechanism concurrently alleviates DOX-associated depressive-like behaviors (Mohammad Abu-Taweel and Al-Fifi, 2021)

LSD1 demethylase represses LPAR6 transcription (56)

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In PCOS, ovarian tissues and GC is characterized by diminished expression of biogenesis regulatorsPGC-1, nuclear respiratory factor 1 (NRF-1) and mitochondrial transcription factor A (TFAM) alongside increased mitochondrial DNA (mtDNA) damage and fragmentation, and ultrastructural abnormalities such as disorganized cristae, swelling, and vacuolization (113)