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It is derived from the C-terminal region of human growth hormone, specifically amino acids 176 to 191, with an additional tyrosine residue at the N-terminus

Pharmacokinetic studies in rats demonstrated an oral bioavailability of 38.4%, with a mean Cmax of 2,252 ng/mL and terminal elimination half-lives of 3.80 1.10 hours (IV) and 6.90 1.20 hours (oral) (Awosemo et al., 2021)

It is essential in the synthesis of proteids (pyridines, purines, etc.)

Symptoms and Signs of Excess Vitamin B12 True vitamin B12 toxicity is exceptionally rare, and when elevated B12 levels are detected, they are often asymptomatic and discovered incidentally during routine blood tests