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They are not approved for human consumption, medical treatment, or veterinary use

The epsilon class GSTE14 in the fruit fly Drosophila melanogaster plays an essential, but as yet mechanistically undefined, role in ecdysteroid hormone biosynthesis (Chanut-Delalande et al., 2014

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Their work found and described several selective NNMT inhibitors, including 5-amino-1-methylquinolinium derivatives