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Trientine is usually recommended second-line in patients intolerant of penicillamine (see Table)[3,1417]

CCK8 assays demonstrated that the therapeutic effects of Nala against DON-induced toxicity were abolished under both treatment conditions (Fig

If intracranial pressure is more than 20 mm Hg or cerebral perfusion pressure less than 60 mm Hg, the following steps are advised: elevation of the head to 20, hyperventilation to a Paco2 of 25 mm Hg, and administration of mannitol (if kidney function is intact)

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