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It is crucial to have peels performed by a qualified professional to avoid potential complications such as burns, scarring, or hyperpigmentation

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Lactate activates collagen prolylhydroxylase, which is an enzyme that governs procollagen hydroxylation and collagen maturation in fibroblasts, thereby enhancing collagen synthesis (Porporato et al., 2012)

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One theoretical advantage of GRF is that it might induce a long-term increase in pituitary GH secretion beyond the duration of therapy, but this was not shown to be the case by our study, and treatment effect is clearly limited to treatment duration, as is the case with GH