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These interactions make the role of ferroptosis in human diseases more complicated and variable

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Whereas these drugs can reduce the frequency of clinical relapses, they do not prevent MS progression and clinical decline, likely due to the continued impairment in remyelination and consequent axonal dysfunction and loss

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The D-Retro-Inverso modification ensures the peptide maintains its binding affinity while resisting proteolytic degradation, allowing extended therapeutic activity for senescent cell targeting in complex tissue environments

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